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But in practice, and especially with regard to synthetic and recombinant peptide forms, there are some considerable potential safety concerns: Immunogenicity Most notably, per a 2020 assessment on therapeutic peptide safety, synthetic and recombinant peptides pose the risk of immunogenicity the ability of a substance to provoke an immune response.15 An immunogenicity-inducing peptide, when introduced to the body, would cause the bodys immune system to perceive the peptide not as a medication but as a threat
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In addition, several clinical trials have been conducted to examine the effect of FMT on IBD, and application has been studied both as a treatment to induce remission and to maintain it, with promising but not entirely satisfactory results, especially when considered on large cohorts
