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91,114,263,423,450,451 The caspase-1-independent pathways of IL-1 production, including the specific proteases involved and the stimuli for their activation, are still not well-defined

Overall, we found that CAR T cells in post-infusion BM samples from LTR have high levels of mTOR signaling, high metabolic polyfunctionality, and an effector immunometabolic profile, and that the BM microenvironmental milieu of LTR may promote mTOR activity for improved anti-tumor activity

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Next, the protein was eluted using LDOX elution buffer (20 mM potassium phosphate, 200 mM NaCl, 2.5 mM d -desthiobiotin, pH 7.4) and the fractions were combined according to the recorded absorption 280 nm ( A 280nm )

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