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[1] Unlike amphetamine abuse, where drug tolerance necessitates escalating doses to achieve the same effect, tolerance to clinically relevant doses of amphetamine plateaus after the initial titration period, and "drug holidays" (i.e., temporary treatment discontinuation) are not required to prevent the development of tolerance

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To Sheriff Bill Snyder's offer to help, Rouse said DOH was, "in the initial phases of the collaboration with an initial meeting set for the near future where local officials will catch detectives up to speed on what health officials have been working on before they're given tasks.LEAH VOSS/TCPALMRenay Rouse, spokeswoman for the Martin County Department of Health, hosted a conversation about hepatitis A with community members and representatives from local organizations Wednesday, April 24, 2019, during the quarterly United Way of Martin County Community Conversations event at First United Methodist Church in Stuart