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In addition, treatment with L-buthionine-sulfoximine (BSO) to deplete glutathione decreased the ESCC tumor burden in mice, thus demonstrating the critical role of glutathione metabolism in ESCC progression

Journal of the American Pharmacists Association: JAPhA, 64 (1), 133138

The spacer length is carefully optimized to allow simultaneous engagement of the peptide with its target receptors while facilitating albumin binding through the fatty acid component

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